p605fig16.39 Data showing effects of medial septum (MS) inactivation on grid cells and network theta oscillations in medial entorhinal cortex (MEC). (A) Examples of disruption in the spatial expression of the hexagonal grid structure for two grid cells (Brandon etal 2011). (B) Temporal reduction in the power and frequency of network theta oscillations (Koenig etal 2011). (C) Temporary reduction in the gridness score, mean firing rate, and patial stability of grid cells (Koenig etal 2011).
|| Disruptive effects of Medial Septum inactivation in Medial Entorhinal Cortex (Brandon etal 2011; Koenig etal 2011). (A) Rate map [rate map, spatial autocorrelations, trajectory] vs [baseline, sub-sampled, medial septum inactivation, 3-6 hour recovery, 24 hour recovery], [rate map (Hz- m, p), spatial autocorrelations (gridness)][ 1.2, 7.2, 1.1; 0.25, 1.7, 0.6; 0.25, 2.5, -0.53; 0.7, 5.1, 0.55; 1.0, 5.3, 1.3; 2.1, 15, 0.19; 1.7, 12, 0.71; 1.7, 3.2, -0.22; 1.8, 9.1, 0.68; 2.5, 13, 0.46]. (B) [normalized power at 7-9 Hz, frequency (Hz)] vs 5-minute periods. (C) [mean gridness score (+-SEM), mean firing rate (% of baseline), mean correlation coeff (+-SEM)] vs 10-minute periods.