p560fig15.29 Excitatory pathways that support activation of the SNc by a US and the conditioning of a CS to the US.
|| Excitatory pathway. Primary reward (apple juice) briefly excites lateral hypothalamus. Hypothalamic-PPTN excitation causes SNc dopamine burst. Hypothalamic activity excites ventral striatum for training. Active CS working memory signals learn to excite ventral striatum. Lateral hypothalamus (Primary Reward Input)-> [(+)ventral striatum <-> ventral pallidium(+)-> PPTN(+)-> SNc]. SNc-> [dopamine signal -> ventral striatum. Conditioned Stimuli working memory trace (CS)(+)-> ventral striatum.